Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389434 | 1.00 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL4780171 | 1.00 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL17545258 | 0.85 | CYP2D6 (0.44) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL6367245 | 0.84 | AKR1C3 (0.51) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL31038326 | 0.84 | AKR1C3 (0.51) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL6367244 | 0.84 | AKR1C3 (0.51) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL3448868 | 0.84 | AKR1C3 (0.51) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL6898435 | 0.83 | AKR1C3 (0.48) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL28456605 | 0.83 | L3MBTL1 (0.53) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL2318137 | 0.83 | AKR1C3 (0.69) | AKR1C3AKR1C2AKR1C1PTGS1UGT2B7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1932852-A1 | Novel taxane related peptides and uses thereof | Campiani, Giuseppe (IT) | 2008-06-18 | — | — | EP | claimed |
| EP-1932852-A1 | Novel taxane related peptides and uses thereof | Campiani, Giuseppe (IT) | 2008-06-18 | — | — | EP | disclosed |