Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 2/20 | 0.41 |
| ▸ | MC5R | P33032 | 2/20 | 0.41 |
| ▸ | MC3R | P41968 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321098 | 0.85 | AKR1C3 (0.51) | AKR1C3AKR1C2HDAC1HDAC8AKR1C1 | |
| SCHEMBL11319751 | 0.84 | AKR1C3 (0.50) | AKR1C3AKR1C2HDAC1HDAC8AKR1C1 | |
| SCHEMBL2536993 | 0.84 | AKR1C3 (0.50) | AKR1C3AKR1C2HDAC1HDAC8AKR1C1 | |
| SCHEMBL2545036 | 0.84 | AKR1C3 (0.50) | AKR1C3AKR1C2HDAC1HDAC8AKR1C1 | |
| SCHEMBL11316020 | 0.84 | AKR1C3 (0.50) | AKR1C3AKR1C2HDAC1HDAC8AKR1C1 | |
| SCHEMBL7799567 | 0.84 | AKR1C3 (0.52) | AKR1C3AKR1C2HDAC1HDAC8AKR1C1 | |
| SCHEMBL4780171 | 0.83 | SLC6A2 (0.55) | AKR1C3AKR1C2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7389434 | 0.83 | SLC6A2 (0.55) | AKR1C3AKR1C2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4778619 | 0.83 | SLC6A2 (0.55) | AKR1C3AKR1C2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5322781 | 0.82 | HRH1 (0.52) | CPB2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040146473-A1 | Self-stabilized; containing (meth)acrylate polysiloxane | L'OREAL (FR) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040146473-A1 | Self-stabilized; containing (meth)acrylate polysiloxane | ACR, MMAB, PDS5A | AKR1C3 3398/4885AKR1C2 3278/4885HDAC1 2146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.