Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777085 | 0.84 | CACNA2D1 (0.40) | KDM4EALDH1A1HPGDGLACASP1 | |
| SCHEMBL3716302 | 0.73 | HRH1 (0.56) | SLC6A2TDP1HRH1NISCH | |
| SCHEMBL12473354 | 0.71 | KDM1A (0.49) | ALDH1A1HPGDNQO2OPRM1KCNH2 | |
| SCHEMBL4778639 | 0.71 | SLC2A1 (0.48) | KDM4EALDH1A1HPGDGLACASP1 | |
| SCHEMBL3887726 | 0.70 | CACNA2D1 (0.41) | KDM4EALDH1A1HPGDGLACASP1 | |
| SCHEMBL28241436 | 0.68 | KDM4E (0.55) | KDM4EALDH1A1HPGDGLACASP1 | |
| SCHEMBL6266749 | 0.67 | KDM4E (0.53) | KDM4EALDH1A1HPGDGLACASP1 | |
| Hydrochloric Acid SCHEMBL3299437 | 0.67 | RAB9A (0.50) | KDM4EALDH1A1HPGDGLACASP1 | |
| SCHEMBL17423904 | 0.67 | KDM4E (0.50) | KDM4EALDH1A1HPGDGLACASP1 | |
| SCHEMBL1102408 | 0.67 | KDM4E (0.50) | KDM4EALDH1A1HPGDGLACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010984-A9 | ACRIDINE ACTIVATION OF P53 AND USES THEREOF | UNIV PENNSYLVANIA (US) | 2008-03-06 | — | — | WO | disclosed |
| WO-2008010984-A2 | ACRIDINE ACTIVATION OF P53 AND USES THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-01-24 | — | — | WO | disclosed |