Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 2/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 4/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777093 | 0.84 | CACNA2D1 (0.52) | TOP2A | |
| SCHEMBL27985054 | 0.78 | KDM4E (0.44) | RAB9ANPC1POLBRAD52KMT2A | |
| SCHEMBL13739508 | 0.76 | CACNA2D1 (0.41) | SLC2A1RAB9ANPC1POLBAPOBEC3A | |
| Hydrochloric Acid SCHEMBL3299437 | 0.74 | RAB9A (0.50) | RAB9APOLBRAD52KMT2ANUDT1 | |
| SCHEMBL4506098 | 0.73 | HTR2A (0.67) | HTR2AHRH1CFDKDM4ECHRM2 | |
| SCHEMBL2680525 | 0.73 | HTR2A (0.67) | HTR2AHRH1CFDKDM4ECHRM2 | |
| SCHEMBL14810439 | 0.71 | KDM4E (0.51) | RAB9ANPC1POLBKMT2AHTR2A | |
| SCHEMBL6266749 | 0.71 | KDM4E (0.53) | SLC2A1RAB9ANPC1POLBAPOBEC3A | |
| SCHEMBL4778635 | 0.71 | KDM4E (0.40) | SLC2A1RAB9ANPC1POLBAPOBEC3A | |
| SCHEMBL28241436 | 0.68 | KDM4E (0.55) | RAB9APOLBRAD52KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010984-A9 | ACRIDINE ACTIVATION OF P53 AND USES THEREOF | UNIV PENNSYLVANIA (US) | 2008-03-06 | — | — | WO | disclosed |
| WO-2008010984-A2 | ACRIDINE ACTIVATION OF P53 AND USES THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-01-24 | — | — | WO | disclosed |