Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 8/20 | 0.39 |
| ▸ | THRB | P10828 | 8/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778737 | 1.00 | MAOA (0.41) | MAOAMAOBALDH1A1HSD17B10KDM4E | |
| SCHEMBL4253926 | 0.93 | MAOA (0.45) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL4253929 | 0.93 | MAOA (0.45) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL4261209 | 0.84 | MAOA (0.47) | MAOAMAOBTHRATHRBPLA2G2A | |
| SCHEMBL4261211 | 0.84 | MAOA (0.47) | MAOAMAOBTHRATHRBPLA2G2A | |
| SCHEMBL4251894 | 0.84 | ALDH1A1 (0.55) | MAOAMAOBALDH1A1HSD17B10KDM4E | |
| SCHEMBL24392404 | 0.79 | KDM4E (0.46) | ALDH1A1HSD17B10KDM4EHPGDGLA | |
| SCHEMBL29262921 | 0.79 | KDM4E (0.46) | ALDH1A1HSD17B10KDM4EHPGDGLA | |
| SCHEMBL29589039 | 0.79 | KDM4E (0.46) | ALDH1A1HSD17B10KDM4EHPGDGLA | |
| SCHEMBL11153695 | 0.79 | ALDH1A1 (0.55) | MAOAMAOBALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986646-A1 | NOVEL AZACYCLY-SUBSTITUTED ARYLTHIENOPYRIMIDINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | Sanofi-Aventis (FR) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093363-A1 | NOVEL AZACYCLY-SUBSTITUTED ARYLTHIENOPYRIMIDINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | SANOFI-AVENTIS (DE) | 2007-08-23 | — | — | WO | disclosed |