Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794417 | 0.85 | POLB (0.40) | MAPTMEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL4779142 | 0.85 | HTR6 (0.39) | HTR2AHTR2CMAPTMEN1KMT2A | |
| SCHEMBL948941 | 0.82 | EDNRA (0.43) | HTR2AHTR2CHTR2BMAPTALDH1A1 | |
| SCHEMBL4778319 | 0.81 | MGAM (0.42) | MEN1KMT2AALDH1A1POLBGAA | |
| SCHEMBL950480 | 0.79 | HTR2A (0.55) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL948778 | 0.79 | MAPT (0.61) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL950574 | 0.78 | MAPT (0.55) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL4769973 | 0.77 | HTR2B (0.52) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL946609 | 0.76 | SMN1; SMN2 (0.58) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL948641 | 0.76 | HTR2A (0.51) | HTR2AHTR2CHTR2BMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581492-B1 | N-ARYLSULFONYL-3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2008-07-16 | — | — | EP | disclosed |