Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MGAM | O43451 | 3/20 | 0.38 |
| ▸ | SI | P14410 | 3/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794417 | 0.87 | POLB (0.40) | HTR6GAAMGAMSIMGAM2 | |
| SCHEMBL4779072 | 0.85 | HTR2A (0.47) | GAAPOLBHTR2AHTR2CMEN1 | |
| SCHEMBL948941 | 0.84 | EDNRA (0.43) | GAAMGAMSIMGAM2POLB | |
| SCHEMBL4778319 | 0.83 | MGAM (0.42) | GAAMGAMSIMGAM2POLB | |
| SCHEMBL949420 | 0.78 | POLB (0.56) | HTR6F7F3GAAMGAM | |
| SCHEMBL947298 | 0.75 | F7 (0.48) | F7F3GAAMGAMSI | |
| SCHEMBL947552 | 0.74 | POLB (0.44) | F7F3GAAMGAMSI | |
| SCHEMBL950579 | 0.73 | GUSB (0.47) | F7F3GAAMGAMSI | |
| SCHEMBL950402 | 0.73 | HTR1A (0.43) | HTR6F7F3POLBDUSP3 | |
| SCHEMBL950364 | 0.73 | MEN1 (0.56) | POLBDUSP3PTPN5PTPN11HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581492-B1 | N-ARYLSULFONYL-3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2008-07-16 | — | — | EP | disclosed |