Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 5/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | DDT | P30046 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 9/20 | 0.33 |
| ▸ | RAF1 | P04049 | 8/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783784 | 0.93 | TEK (0.40) | TEKNR1I2DDTBRAFRAF1 | |
| SCHEMBL4782660 | 0.91 | NR1I2 (0.42) | TEKNR1I2DDTBRAFRAF1 | |
| SCHEMBL4780039 | 0.90 | TEK (0.40) | TEKNR1I2DDTBRAFRAF1 | |
| SCHEMBL4880891 | 0.90 | TEK (0.38) | TEKNR1I2BRAFRAF1 | |
| SCHEMBL4779207 | 0.89 | NR1I2 (0.38) | TEKNR1I2DDTMIF | |
| SCHEMBL14293386 | 0.89 | TEK (0.43) | TEKNR1I2BRAFRAF1 | |
| SCHEMBL4779480 | 0.89 | TEK (0.40) | TEKNR1I2BRAFRAF1 | |
| SCHEMBL4780202 | 0.88 | TEK (0.42) | TEKNR1I2BRAFRAF1 | |
| SCHEMBL4778561 | 0.88 | DDT (0.45) | NR1I2DDT | |
| SCHEMBL4782191 | 0.87 | MEN1 (0.47) | TEKNR1I2BRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |