Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 15/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781101 | 0.90 | EPHX2 (0.51) | EPHX2TRPV1CNR1CHRM1 | |
| SCHEMBL4776335 | 0.87 | TRPV1 (0.53) | EPHX2TRPV1ALDH1A1LMNAHPGD | |
| SCHEMBL4779566 | 0.86 | TRPV1 (0.50) | EPHX2TRPV1CNR1 | |
| SCHEMBL4778894 | 0.84 | EPHX2 (0.49) | EPHX2TRPV1CNR1CHRM1 | |
| SCHEMBL4780962 | 0.83 | KDM4E (0.47) | EPHX2TRPV1CNR1ALDH1A1CHRM1 | |
| SCHEMBL4778063 | 0.83 | CHRM1 (0.48) | EPHX2TRPV1CNR1CHRM1 | |
| SCHEMBL4779491 | 0.82 | TRPV1 (0.51) | EPHX2TRPV1HTTBLM | |
| SCHEMBL4779427 | 0.80 | EPHX2 (0.51) | EPHX2TRPV1CNR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4774265 | 0.80 | TRPV1 (0.52) | EPHX2TRPV1CNR1 | |
| SCHEMBL4780970 | 0.78 | TRPV1 (0.63) | TRPV1ALDH1A1LMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |