SCHEMBL477956

SCHEMBL477956

OCCCC(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL578466 0.90
SCHEMBL7858172 0.87 LMNA (0.38)
SCHEMBL11102876 0.87 LMNA (0.38)
SCHEMBL11101915 0.87 LMNA (0.38)
SCHEMBL574847 0.87
SCHEMBL5416483 0.87 LMNA (0.38)
SCHEMBL4024083 0.79 ALDH1A1 (0.32)
SCHEMBL24823 0.77
SCHEMBL13719304 0.76
SCHEMBL13718881 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348421-A1 5-HT2A RECEPTOR INHIBITOR OR INVERSE AGONIST, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF LUYE INNOMIND PHARMA SHIJIAZHUANG CO., LTD. (CN) 2023-11-02 US claimed
EP-4186893-A1 5-HT2A RECEPTOR INHIBITOR OR INVERSE AGONIST, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Geneora Pharma (Shijiazhuang) Co., Ltd. (CN) 2023-05-31 EP claimed
CN-114728933-A 5-HT2AReceptor inhibitor or inverse agonist, preparation method and application thereof 山东绿叶制药有限公司 2022-07-08 CN claimed
US-20250215025-A1 FLUORINE ATOM CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2025-07-03 US disclosed
CN-120051477-A Silane compound containing fluorine atom 大金工业株式会社 2025-05-27 CN disclosed
EP-3882235-B1 PRODUCTION METHOD FOR ISOCYANATE COMPOUND UNIV KOBE NAT UNIV CORP (JP) 2025-01-22 EP disclosed
US-20240383903-A1 Modulators of STING (Stimulator of Interferon Genes) PFIZER INC. (US) 2024-11-21 US disclosed
CN-116057042-B Acrylamide-substituted indane compounds and their therapeutic uses 赛诺菲 2024-10-18 CN disclosed
US-12060312-B2 Production method for isocyanate compound NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2024-08-13 US disclosed
CN-118176183-A HIF-2 alpha inhibitors and methods of use thereof 艾库斯生物科学有限公司 2024-06-11 CN disclosed
WO-2024101404-A1 FLUORINE ATOM CONTAINING SILANE COMPOUND ダイキン工業株式会社 2024-05-16 WO disclosed
EP-0352123-B1 4-Oxoquinoline-3-carboxylic acid derivatives, their preparation and their use UBE INDUSTRIES (JP) 1995-01-18 EP disclosed
US-5348961-A Antibacterial agents SANKYO COMPANY LIMITED (JP) 1994-09-20 US disclosed
EP-0610958-A2 Intermediates in the preparation of 4-oxoquinoline-3-carboxylic acid derivatives UBE INDUSTRIES, LTD. (JP) 1994-08-17 EP disclosed
US-5270327-A Piperidine derivatives SANKYO COMPANY, LIMITED (JP) 1993-12-14 US disclosed
EP-0356247-B1 ANALGESIC CARBOXYLIC ACID AMIDE DERIVATIVES Sankyo Company Limited (JP) 1993-03-17 EP disclosed
US-5073556-A Bactericides SANKYO COMPANY LIMITED (JP) 1991-12-17 US disclosed
US-5021413-A Analgesic thiomorpholins their preparation, and pharmaceutical compositions containing them SANKYO COMPANY LIMITED (JP) 1991-06-04 US disclosed
EP-0356247-A1 Analgesic carboxylic acid amide derivatives Sankyo Company Limited (JP) 1990-02-28 EP disclosed
EP-0352123-A2 4-Oxoquinoline-3-carboxylic acid derivatives, their preparation and their use UBE INDUSTRIES LIMITED (JP) 1990-01-24 EP disclosed