Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.58 |
| ▸ | RXRB | P28702 | 1/20 | 0.58 |
| ▸ | RXRG | P48443 | 1/20 | 0.58 |
| ▸ | KIF11 | P52732 | 6/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 5/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28222645 | 1.00 | RXRA (0.58) | RXRARXRBRXRGKIF11NOTUM | |
| SCHEMBL28231443 | 0.90 | RXRA (0.54) | RXRARXRBRXRGKIF11NOTUM | |
| SCHEMBL27638533 | 0.83 | S1PR1 (0.52) | RXRARXRBRXRGKIF11AR | |
| SCHEMBL6120541 | 0.83 | KIF11 (0.69) | KIF11CYP11B2 | |
| SCHEMBL4636314 | 0.81 | S1PR1 (0.60) | RXRARXRBRXRGKIF11NOTUM | |
| SCHEMBL1041026 | 0.81 | ESR2 (0.52) | RXRARXRBRXRGKIF11CYP11B2 | |
| SCHEMBL1042573 | 0.81 | NOTUM (0.50) | RXRARXRBRXRGKIF11NOTUM | |
| SCHEMBL1040661 | 0.81 | KIF11 (0.48) | RXRARXRBRXRGKIF11NOTUM | |
| SCHEMBL31570062 | 0.81 | KIF11 (0.57) | RXRARXRBRXRGKIF11CYP11B2 | |
| SCHEMBL3785824 | 0.81 | KIF11 (0.57) | RXRARXRBRXRGKIF11CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075324-A1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-07 | — | — | US | claimed |
| CN-109239816-A | Laminated film, and display device including the same | 三星电子株式会社 | 2019-01-18 | — | — | CN | disclosed |
| CN-103254250-B | Ferrocenyl pyridine cyclic Pd-N heterocyclic carbene compound as well as preparation method and application thereof | UNIV LUOYANG NORMAL | 2015-06-10 | — | — | CN | disclosed |
| US-7368462-B1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2008-05-06 | — | — | US | disclosed |
| US-20080058423-A1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY | 2008-03-06 | — | — | US | disclosed |
| WO-2008001160-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-03 | — | — | WO | disclosed |
| US-7304065-B2 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | disclosed |
| US-20060247239-A1 | Melanin concentrating hormone antagonists | HU XIUFENG E | 2006-11-02 | — | — | US | disclosed |
| EP-1667958-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005033063-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-14 | — | — | WO | disclosed |
| US-20050075324-A1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058423-A1 | Melanin concentrating hormone antagonists | MCHR1, MCHR2, MC4R | RXRA 1066/4885RXRB 1075/4885RXRG 777/4885 |
| US-20050075324-A1 | Melanin concentrating hormone antagonists | MCHR1, MCHR2, MC1R | RXRA 1395/4885RXRB 1565/4885RXRG 1073/4885 |
| US-20060247239-A1 | Melanin concentrating hormone antagonists | MCHR1, MCHR2, MC1R | RXRA 1395/4885RXRB 1565/4885RXRG 1073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.