Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | FABP6 | P51161 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240221 | 0.94 | TYMS (0.60) | TYMSPLAUHTR3EHTR3BHTR3A | |
| SCHEMBL5681591 | 0.94 | TYMS (0.52) | TYMSPLAUHTR3EHTR3BHTR3A | |
| SCHEMBL5679917 | 0.81 | FABP6 (0.47) | TYMSPLAUHTR3EHTR3BHTR3A | |
| SCHEMBL5924403 | 0.81 | BACE1 (0.53) | TYMSPLAUHTR3EHTR3BHTR3A | |
| SCHEMBL12686275 | 0.78 | PLAU (0.58) | TYMSPLAUHTR3EHTR3BHTR3A | |
| SCHEMBL15938795 | 0.78 | ALDH1A1 (0.50) | TYMSPLAUHTR3EHTR3BHTR3A | |
| SCHEMBL3500728 | 0.78 | S1PR4 (0.59) | PLAUHTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL3500724 | 0.78 | ATP4A (0.46) | FABP6ALDH1A1MEN1KMT2AMASP2 | |
| Hydrochloric Acid SCHEMBL23201245 | 0.77 | PLAU (0.56) | TYMSPLAUHTR3EHTR3BHTR3A | |
| SCHEMBL727388 | 0.77 | PLAU (0.61) | TYMSPLAUHTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016666-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-02-07 | — | — | WO | disclosed |