Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716424 | 0.78 | PTGS2 (0.45) | CYP2A6CYP2B6 | |
| SCHEMBL4779961 | 0.77 | — | — | |
| SCHEMBL13879062 | 0.71 | CYP2A6 (0.62) | CYP2A6CYP2B6CYP3A4CYP2C19CYP2E1 | |
| SCHEMBL918324 | 0.71 | DCUN1D1 (0.47) | — | |
| SCHEMBL4781868 | 0.71 | NOTUM (0.33) | — | |
| SCHEMBL7429132 | 0.70 | ESR1 (0.32) | — | |
| SCHEMBL4782555 | 0.69 | — | — | |
| SCHEMBL14440820 | 0.69 | POLB (0.34) | — | |
| SCHEMBL8987547 | 0.68 | HPGD (0.42) | — | |
| SCHEMBL4783020 | 0.68 | PLA2G10 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | claimed |
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | disclosed |