SCHEMBL4781868

SCHEMBL4781868

Cc1c[nH]cc1-c1nnn[nH]1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL918324 0.76 DCUN1D1 (0.47) NOTUM
SCHEMBL5813250 0.73 P2RX7 (0.39)
SCHEMBL27761643 0.73 GAA (0.44) NOTUM
Hydrochloric Acid SCHEMBL27741149 0.72 GAA (0.43) NOTUM
SCHEMBL12615990 0.72 ALDH1A1 (0.38)
SCHEMBL4782555 0.71
SCHEMBL14440820 0.71 POLB (0.34)
SCHEMBL4779968 0.71 CYP2A6 (0.38)
SCHEMBL27362947 0.69 NPSR1 (0.34)
Trimethylammonium SCHEMBL27761683 0.69 GAA (0.41) NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008031888-A2 CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS CAMPIANI GIUSEPPE (IT) 2008-03-20 WO disclosed