Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HRH1 | P35367 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL403460 | 0.87 | CYP1A2 (0.56) | SMN1; SMN2CYP1A2CYP2C19HRH1TDP1 | |
| SCHEMBL9658041 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP1A2CYP2C19HRH1HDAC1 | |
| SCHEMBL2302450 | 0.84 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP1A2CYP2C19HRH1HDAC1 | |
| SCHEMBL7376400 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP1A2CYP2C19HRH1HDAC1 | |
| SCHEMBL2960008 | 0.83 | SMN1; SMN2 (0.64) | SMN1; SMN2CYP1A2CYP2C19HRH1HDAC1 | |
| SCHEMBL7378329 | 0.83 | HRH1 (0.64) | SMN1; SMN2CYP1A2CYP2C19HRH1HDAC1 | |
| SCHEMBL18248625 | 0.83 | HRH1 (0.64) | SMN1; SMN2CYP1A2CYP2C19HRH1HDAC1 | |
| SCHEMBL9237645 | 0.83 | SMN1; SMN2 (0.64) | SMN1; SMN2CYP1A2CYP2C19HRH1HDAC1 | |
| SCHEMBL6245103 | 0.81 | CYP1A2 (0.58) | SMN1; SMN2CYP1A2CYP2C19HRH1HDAC1 | |
| SCHEMBL726512 | 0.81 | HRH1 (0.76) | SMN1; SMN2CYP1A2CYP2C19HRH1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008003746-A1 | N-(4-PYRIDIN-2-YLBUTYL) CARBOXAMIDE DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2008-01-10 | — | — | WO | disclosed |