Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PTPRA | P18433 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780002 | 0.87 | SMN1; SMN2 (0.59) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 | |
| SCHEMBL29499090 | 0.82 | SMN1; SMN2 (0.62) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 | |
| SCHEMBL333243 | 0.82 | SMN1; SMN2 (0.62) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 | |
| SCHEMBL6446039 | 0.82 | CYP1A2 (0.57) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 | |
| Hydrochloric Acid SCHEMBL28672925 | 0.81 | SMN1; SMN2 (0.60) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 | |
| Hydrochloric Acid SCHEMBL4174816 | 0.81 | SMN1; SMN2 (0.60) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 | |
| Lithium Ion SCHEMBL28463950 | 0.81 | CYP1A2 (0.56) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 | |
| SCHEMBL5493166 | 0.81 | SMN1; SMN2 (0.56) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 | |
| SCHEMBL626826 | 0.81 | HRH1 (0.57) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 | |
| SCHEMBL2722250 | 0.81 | ALDH1A1 (0.57) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3558945-B1 | PROCESS FOR THE PREPARATION OF A N-[2-(2-PYRIDINYL)ETHYL]CARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2021-05-05 | — | — | EP | claimed |
| US-10807955-B2 | Process for the preparation of a 2-pyridylethylcarboxamide derivative | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-10-20 | — | — | US | claimed |
| US-20200039937-A1 | PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-06 | — | — | US | claimed |
| EP-3558945-A1 | PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE | Bayer CropScience Aktiengesellschaft (DE) | 2019-10-30 | — | — | EP | claimed |
| WO-2018114484-A1 | PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-06-28 | — | — | WO | claimed |
| JP-4794570-B2 | — | — | 2011-10-19 | — | — | JP | claimed |
| EP-1833793-B1 | PROCESS FOR THE PREPARATION OF A 2-ETHYLAMINOPYRIDINE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2010-12-08 | — | — | EP | claimed |
| US-20100292485-A1 | PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE S.A. (FR) | 2010-11-18 | — | — | US | claimed |
| US-7790901-B2 | N-{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-trifluoromethylbenzamide; starting with a halogenobenzoyl derivative to produce a N-acetoxymethylcarboxamide derivative and then coupling it with a 2-pyridyl acetate derivative; pesticide | BAYER CROPSCIENCE S.A. (FR) | 2010-09-07 | — | — | US | claimed |
| JP-2008524307-A | — | — | 2008-07-10 | — | — | JP | claimed |
| US-20080114176-A1 | Process For The Preparation Of A 2-Ethylaminopyridine Derivative | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-05-15 | — | — | US | claimed |
| US-20080086008-A1 | N-{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-trifluoromethylbenzamide; starting with a halogenobenzoyl derivative to produce a N-acetoxymethylcarboxamide derivative and then coupling it with a 2-pyridyl acetate derivative; pesticide | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-04-10 | — | — | US | claimed |
| EP-1833793-A1 | PROCESS FOR THE PREPARATION OF A 2-ETHYLAMINOPYRIDINE DERIVATIVE | Bayer CropScience S.A. (FR) | 2007-09-19 | — | — | EP | claimed |
| EP-1831169-A2 | PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE | Bayer CropScience S.A. (FR) | 2007-09-12 | — | — | EP | claimed |
| WO-2006067103-A2 | PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE SA (FR) | 2006-06-29 | — | — | WO | claimed |
| WO-2006067106-A1 | PROCESS FOR THE PREPARATION OF A 2-ETHYLAMINOPYRIDINE DERIVATIVE | BAYER CROPSCIENCE SA (FR) | 2006-06-29 | — | — | WO | claimed |
| EP-1674455-A1 | Process for the preparation of a 2-ethylaminopyridine derivative | Bayer CropScience S.A. (FR) | 2006-06-28 | — | — | EP | claimed |
| EP-3558945-B1 | PROCESS FOR THE PREPARATION OF A N-[2-(2-PYRIDINYL)ETHYL]CARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2021-05-05 | — | — | EP | disclosed |
| US-20040077707-A1 | Pyrrole based inhibitors of glycogen synthase kinase 3 | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2004-04-22 | — | — | US | disclosed |
| WO-2004018455-A1 | PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10807955-B2 | Process for the preparation of a 2-pyridylethylcarboxamide derivative | CPS1, PLPBP, CYP4F2 | CYP1A2 39/4885SMN1; SMN2 952/4885CYP2C19 28/4885 |
| US-20080086008-A1 | N-{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-trifluoromethylbenzamide; starting with a halogenobenzoyl derivative to produce a N-acetoxymethylcarboxamide derivative and then coupling it with a 2-pyridyl acetate derivative; pesticide | DDT, PFAS, AADAC | CYP1A2 27/4885SMN1; SMN2 1857/4885CYP2C19 254/4885 |
| US-20080114176-A1 | Process For The Preparation Of A 2-Ethylaminopyridine Derivative | SDHA, UROD, SDHB | CYP1A2 16/4885SMN1; SMN2 1165/4885CYP2C19 4/4885 |
| US-20200039937-A1 | PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE | CPS1, CYP4F2, PLPBP | CYP1A2 41/4885SMN1; SMN2 805/4885CYP2C19 29/4885 |
| US-20040077707-A1 | Pyrrole based inhibitors of glycogen synthase kinase 3 | GSK3B, GSK3A, PYGB | CYP1A2 2679/4885SMN1; SMN2 4203/4885CYP2C19 2462/4885 |
| US-20100292485-A1 | PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE | GBA2, CPS1, CYP4F2 | CYP1A2 38/4885SMN1; SMN2 1099/4885CYP2C19 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.