Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 3/20 | 0.33 |
| ▸ | KIF11 | P52732 | 3/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029041 | 0.90 | KDM4E (0.38) | OPRM1OPRD1KDM2BMEN1KMT2A | |
| SCHEMBL4772059 | 0.89 | OPRM1 (0.35) | OPRM1OPRD1KDM2BMEN1KMT2A | |
| SCHEMBL4027446 | 0.89 | OPRM1 (0.35) | OPRM1OPRD1KDM2BMEN1KMT2A | |
| SCHEMBL4027439 | 0.89 | OPRM1 (0.35) | OPRM1OPRD1KDM2BMEN1KMT2A | |
| SCHEMBL4779051 | 0.88 | KDM4E (0.36) | OPRM1OPRD1KDM2BMEN1KMT2A | |
| SCHEMBL13720775 | 0.87 | MEN1 (0.35) | OPRM1OPRD1KDM2BMEN1KMT2A | |
| SCHEMBL4024540 | 0.87 | MEN1 (0.35) | OPRM1OPRD1KDM2BMEN1KMT2A | |
| SCHEMBL4024525 | 0.87 | MEN1 (0.35) | OPRM1OPRD1KDM2BMEN1KMT2A | |
| SCHEMBL4020633 | 0.87 | MEN1 (0.35) | OPRM1OPRD1KDM2BMEN1KMT2A | |
| SCHEMBL4028045 | 0.87 | OPRM1 (0.35) | OPRM1OPRD1KDM2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |