Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10867874 | 0.83 | AHR (0.48) | AHRSLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL254524 | 0.80 | AHR (0.50) | AHRSLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL5862322 | 0.76 | ADRB2 (0.56) | AHRSLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL2951028 | 0.76 | AHR (0.46) | AHRSLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL1988446 | 0.76 | AHR (0.46) | AHRSLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL4458063 | 0.76 | AHR (0.46) | AHRSLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL17084188 | 0.76 | AHR (0.46) | AHRSLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL22032277 | 0.76 | AHR (0.46) | AHRSLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL22964332 | 0.76 | AHR (0.46) | AHRSLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL3181409 | 0.76 | ADRB2 (0.56) | AHRSLC6A4SLC6A2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931620-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIQUIDS | Sanofi-Aventis (FR) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007034252-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIQUIDS | SANOFI-AVENTIS (FR) | 2007-03-29 | — | — | WO | disclosed |