Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1463109 | 0.85 | KDM4E (0.46) | ADORA1ADORA2ACYP19A1MEN1KMT2A | |
| SCHEMBL21116203 | 0.83 | USP8 (0.42) | GSK3AGSK3B | |
| SCHEMBL20114501 | 0.83 | ADORA1 (0.46) | ADORA1ADORA2AMEN1KMT2ASQOR | |
| SCHEMBL21022649 | 0.82 | ESR2 (0.44) | ADORA1ADORA2AESR2AR | |
| SCHEMBL20843322 | 0.82 | ADORA1 (0.45) | ADORA1ADORA2AMEN1KMT2ASQOR | |
| SCHEMBL15420921 | 0.81 | ESR2 (0.58) | CYP19A1ESR2GSK3AGSK3BAR | |
| SCHEMBL9374553 | 0.81 | AR (0.46) | SQORALDH1A1KDM4EGAAGSK3A | |
| SCHEMBL2649762 | 0.81 | GRM5 (0.41) | ADORA1ADORA2ANPSR1KDM4EHPGD | |
| SCHEMBL2650791 | 0.81 | KDM4E (0.43) | ADORA1ADORA2AMEN1KMT2ANPSR1 | |
| SCHEMBL24927807 | 0.81 | CYP11B1 (0.44) | ADORA1ADORA2ASQORNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667958-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-14 | — | — | EP | claimed |
| WO-2005033063-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-14 | — | — | WO | claimed |
| US-20050075324-A1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-07 | — | — | US | claimed |
| CN-114560790-B | Biphenyl-2-nitrile compound and preparation method thereof | 赣南师范大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-114560790-A | Biphenyl-2-nitrile compound and preparation method thereof | 赣南师范大学 | 2022-05-31 | — | — | CN | disclosed |
| US-11124521-B2 | Condensed cyclic compound and organic light-emitting device including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2021-09-21 | — | — | US | disclosed |
| US-20190315760-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMNITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2019-10-17 | — | — | US | disclosed |
| WO-2008001160-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-03 | — | — | WO | disclosed |
| US-7304065-B2 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | disclosed |
| US-20060247239-A1 | Melanin concentrating hormone antagonists | HU XIUFENG E | 2006-11-02 | — | — | US | disclosed |
| EP-1667958-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005033063-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-14 | — | — | WO | disclosed |
| US-20050075324-A1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075324-A1 | Melanin concentrating hormone antagonists | MCHR1, MCHR2, MC1R | ADORA1 317/4885ADORA2A 194/4885CYP19A1 205/4885 |
| US-20060247239-A1 | Melanin concentrating hormone antagonists | MCHR1, MCHR2, MC1R | ADORA1 317/4885ADORA2A 194/4885CYP19A1 205/4885 |
| US-11124521-B2 | Condensed cyclic compound and organic light-emitting device including the same | CRY1, CRY2, CCNT1 | ADORA1 4034/4885ADORA2A 4646/4885CYP19A1 48/4885 |
| US-20190315760-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMNITTING DEVICE INCLUDING THE SAME | CCNT1, CRY1, CCNT2 | ADORA1 4248/4885ADORA2A 4657/4885CYP19A1 289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.