Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 10/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 3/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3761241 | 0.88 | PIK3CG (0.44) | NOS1PIK3CGPIK3CA | |
| SCHEMBL3765540 | 0.85 | MPO (0.38) | NOS1PIK3CGFEN1ALOX5APMPO | |
| SCHEMBL4408579 | 0.79 | NOS1 (0.50) | NOS1PIK3CGMPOPIK3CA | |
| SCHEMBL3755253 | 0.77 | GRIN2B (0.39) | NOS1PIK3CGMPOPIK3CA | |
| SCHEMBL3764007 | 0.77 | TLR8 (0.39) | NOS1PIK3CGMPOPIK3CA | |
| SCHEMBL3760895 | 0.77 | MPO (0.40) | NOS1PIK3CGMPOPIK3CAMAPT | |
| SCHEMBL3764015 | 0.75 | NOS1 (0.46) | NOS1PIK3CGMPOPIK3CA | |
| SCHEMBL3759861 | 0.75 | PIK3CG (0.49) | NOS1PIK3CGPIK3CA | |
| SCHEMBL4452143 | 0.75 | NOS1 (0.50) | NOS1PIK3CGMPOPIK3CANPC1 | |
| SCHEMBL3760590 | 0.74 | NEK2 (0.45) | NOS1PIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009079-A2 | SUBSTITUTED PTERIDINES USEFUL FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-01-24 | — | — | WO | claimed |