Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780473 | 1.00 | ALDH1A1 (0.38) | ALDH1A1CYP2E1PDE4DKDM4EGAA | |
| SCHEMBL4795648 | 0.93 | ALDH1A1 (0.37) | ALDH1A1PDE4DKDM4E | |
| SCHEMBL4795652 | 0.93 | ALDH1A1 (0.37) | ALDH1A1PDE4DKDM4E | |
| SCHEMBL4779299 | 0.93 | CYP2E1 (0.33) | ALDH1A1CYP2E1PDE4DGAA | |
| SCHEMBL4779290 | 0.93 | CYP2E1 (0.33) | ALDH1A1CYP2E1PDE4DGAA | |
| SCHEMBL4844784 | 0.87 | PDE4D (0.35) | ALDH1A1PDE4DKDM4EGAA | |
| SCHEMBL4844797 | 0.87 | PDE4D (0.35) | ALDH1A1PDE4DKDM4EGAA | |
| SCHEMBL4726527 | 0.87 | ALDH1A1 (0.39) | ALDH1A1CYP2E1KDM4E | |
| SCHEMBL4726531 | 0.87 | ALDH1A1 (0.39) | ALDH1A1CYP2E1KDM4E | |
| SCHEMBL4147221 | 0.84 | PDE4D (0.34) | PDE4DL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017688-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-14 | — | — | WO | claimed |
| WO-2008017688-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-14 | — | — | WO | disclosed |