Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21887785 | 1.00 | CTSD (0.48) | CTSDHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL16658608 | 0.88 | FAAH (0.55) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL5983514 | 0.86 | FAAH (0.63) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9666212 | 0.86 | FAAH (0.63) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9666241 | 0.84 | FAAH (0.67) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9666209 | 0.84 | FAAH (0.67) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9664202 | 0.84 | FAAH (0.67) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL21587875 | 0.84 | FAAH (0.67) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9665588 | 0.84 | FAAH (0.67) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL7519265 | 0.84 | FAAH (0.67) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045671-A1 | MATRIX METALLOPROTEASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-04-17 | — | — | WO | disclosed |