Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583335 | 0.88 | MEN1 (0.55) | MALT1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4583601 | 0.88 | KMT2A (0.52) | MALT1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4582961 | 0.85 | MALT1 (0.51) | MALT1KMT2AMEN1DRD2DRD4 | |
| SCHEMBL4581567 | 0.85 | MALT1 (0.45) | MALT1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL4725020 | 0.85 | MAPT (0.44) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL4779982 | 0.83 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL4729793 | 0.83 | MALT1 (0.40) | MALT1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4583157 | 0.82 | MALT1 (0.51) | MALT1ALDH1A1MAPT | |
| SCHEMBL4726520 | 0.78 | KMT2A (0.40) | MALT1KMT2AALDH1A1 | |
| SCHEMBL4582822 | 0.78 | ALDH1A1 (0.51) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008028690-A1 | 1-(HET)ARYL-3-[HETARYL-PIPERIDIN-4-YL]-THIOUREAS AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |