Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780004 | 0.90 | NOTUM (0.46) | NOTUMKDM4CKDM4AKDM2BMEN1 | |
| SCHEMBL4783495 | 0.88 | CHRM2 (0.51) | NOTUMMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL7833793 | 0.84 | EPHX2 (0.46) | NOTUMKDM4CKDM4AKDM2BMEN1 | |
| SCHEMBL3014379 | 0.81 | NOTUM (0.46) | NOTUMKDM4CKDM4AKDM2BMEN1 | |
| Ammonia Solution, Strong SCHEMBL4926298 | 0.79 | NOTUM (0.49) | NOTUMKDM4CKDM4AKDM2BMEN1 | |
| SCHEMBL4782528 | 0.78 | CHRM2 (0.54) | NOTUMKDM4CKDM4AKDM2BMEN1 | |
| SCHEMBL24823574 | 0.77 | NOTUM (0.49) | NOTUMKDM4CKDM4AKDM2BMEN1 | |
| SCHEMBL3467262 | 0.77 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL12060492 | 0.77 | NOTUM (0.53) | NOTUMKDM4CKDM4AKDM2BALDH1A1 | |
| SCHEMBL8657106 | 0.72 | CHRM2 (0.51) | KDM4CKDM4AKDM2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008042735-A1 | TETRAHYDROQUINOLINE, INDOLINE, AND RELATED ANILINE DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXAN METHYLAMINES | WYETH (US) | 2008-04-10 | — | — | WO | disclosed |