Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782528 | 0.90 | CHRM2 (0.54) | CHRM2CHRM3ALDH1A1MEN1KMT2A | |
| SCHEMBL4780942 | 0.88 | NOTUM (0.44) | CHRM2CHRM3ALDH1A1MEN1KMT2A | |
| SCHEMBL8657106 | 0.84 | CHRM2 (0.51) | CHRM2CHRM3ALDH1A1MEN1KMT2A | |
| SCHEMBL4572835 | 0.81 | CHRM2 (0.54) | CHRM2CHRM3ALDH1A1MEN1KMT2A | |
| SCHEMBL19173539 | 0.81 | CHRM2 (0.54) | CHRM2CHRM3ALDH1A1MEN1KMT2A | |
| SCHEMBL4780004 | 0.78 | NOTUM (0.46) | CHRM2CHRM3ALDH1A1MEN1KMT2A | |
| SCHEMBL20348513 | 0.77 | CHRM2 (0.56) | CHRM2CHRM3ALDH1A1MEN1KMT2A | |
| SCHEMBL30335825 | 0.77 | CHRM2 (0.56) | CHRM2CHRM3ALDH1A1MEN1KMT2A | |
| SCHEMBL3467262 | 0.77 | ALDH1A1 (0.72) | CHRM2CHRM3ALDH1A1MEN1KMT2A | |
| SCHEMBL22225699 | 0.75 | CHRM2 (0.58) | CHRM2CHRM3ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008042735-A1 | TETRAHYDROQUINOLINE, INDOLINE, AND RELATED ANILINE DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXAN METHYLAMINES | WYETH (US) | 2008-04-10 | — | — | WO | disclosed |