Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 17/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780953 | 1.00 | KDM4E (0.44) | KDM4EALDH1A1MAPTSMN1; SMN2TRPV1 | |
| SCHEMBL4777153 | 0.80 | TRPV1 (0.51) | TRPV1CYP3A4 | |
| SCHEMBL4777937 | 0.79 | TRPV1 (0.58) | ALDH1A1MAPTTRPV1CYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL4780347 | 0.77 | TRPV1 (0.58) | KDM4EALDH1A1MAPTTRPV1CYP3A4 | |
| SCHEMBL4778211 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1MAPTSMN1; SMN2TRPV1 | |
| SCHEMBL4779521 | 0.75 | TRPV1 (0.55) | KDM4EALDH1A1MAPTSMN1; SMN2TRPV1 | |
| SCHEMBL4778198 | 0.74 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL4778200 | 0.74 | TRPV1 (0.55) | KDM4EALDH1A1MAPTSMN1; SMN2TRPV1 | |
| SCHEMBL4776317 | 0.72 | TRPV1 (0.60) | KDM4EALDH1A1MAPTSMN1; SMN2TRPV1 | |
| SCHEMBL4779001 | 0.72 | TRPV1 (0.49) | KDM4EALDH1A1MAPTTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | claimed |
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |