Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 6/20 | 0.95 |
| ▸ | CPT2 | P23786 | 1/20 | 0.95 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL4780983 | 1.00 | ACLY (0.95) | ACLYCPT2HSPD1BLMHSPE1 | |
| Ammonia Solution, Strong SCHEMBL1469558 | 0.98 | ACLY (0.91) | ACLYCPT2HSPD1BLMHSPE1 | |
| Ammonia Solution, Strong SCHEMBL27593651 | 0.98 | ACLY (0.91) | ACLYCPT2HSPD1BLMHSPE1 | |
| SCHEMBL17181773 | 0.98 | ACLY (1.00) | ACLYCPT2HSPD1BLMHSPE1 | |
| SCHEMBL6773065 | 0.98 | ACLY (1.00) | ACLYCPT2HSPD1BLMHSPE1 | |
| SCHEMBL2111332 | 0.98 | ACLY (1.00) | ACLYCPT2HSPD1BLMHSPE1 | |
| SCHEMBL2110910 | 0.98 | ACLY (1.00) | ACLYCPT2HSPD1BLMHSPE1 | |
| SCHEMBL721435 | 0.98 | ACLY (1.00) | ACLYCPT2HSPD1BLMHSPE1 | |
| SCHEMBL108615 | 0.98 | ACLY (1.00) | ACLYCPT2HSPD1BLMHSPE1 | |
| SCHEMBL17181757 | 0.98 | ACLY (1.00) | ACLYCPT2HSPD1BLMHSPE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050282894-A1 | Hydroxycitric acid compositions, pharmaceutical and dietary supplements and food products made therefrom, and methods for their use in reducing body weight | INTERHEALTH NUTRACEUTICALS, INC. (US) | 2005-12-22 | — | — | US | claimed |
| WO-2008008837-A2 | A METHOD OF INCREASING TRYPTOPHAN AND NICOTINAMIDE LEVELS IN VIVO | LYNPETE TRADING 6 (PTY) LTD. TRADING AS GENETIC HEALTH ENTERPRISES (ZA) | 2008-01-17 | — | — | WO | disclosed |
| EP-1858500-A2 | MEDICINAL COMPOSITIONS OF SALTS, CHELATES AND/OR FREE ACIDS OF ALPHA HYDROXYL ORGANIC ACIDS AND RELATED PROCESSES AND METHODS | Pero, Ronald W. (SE) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006101922-A2 | MEDICINAL COMPOSITIONS OF SALTS, CHELATES AND/OR FREE ACIDS OF ALPHA HYDROXYL ORGANIC ACIDS AND RELATED PROCESSES AND METHODS | PERO RONALD W (SE) | 2006-09-28 | — | — | WO | disclosed |