SCHEMBL6773065

SCHEMBL6773065

O=C(O)C[C@@](O)(C(=O)O)[C@H](O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACLY P53396 6/20 1.00
CPT2 P23786 1/20 1.00
HSPD1 P10809 1/20 0.46
BLM P54132 1/20 0.46
HSPE1 P61604 1/20 0.46
ALDH1A1 P00352 1/20 0.44
HMGCR P04035 1/20 0.39
CHRM1 P11229 1/20 0.39
TBXA2R P21731 1/20 0.39
ADRA1A P35348 1/20 0.39
CYP2D6 P10635 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2111332 1.00 ACLY (1.00) ACLYCPT2HSPD1BLMHSPE1
SCHEMBL721435 1.00 ACLY (1.00) ACLYCPT2HSPD1BLMHSPE1
SCHEMBL17181773 1.00 ACLY (1.00) ACLYCPT2HSPD1BLMHSPE1
SCHEMBL17181757 1.00 ACLY (1.00) ACLYCPT2HSPD1BLMHSPE1
SCHEMBL2110910 1.00 ACLY (1.00) ACLYCPT2HSPD1BLMHSPE1
SCHEMBL27688847 1.00 ACLY (1.00) ACLYCPT2HSPD1BLMHSPE1
SCHEMBL108615 1.00 ACLY (1.00) ACLYCPT2HSPD1BLMHSPE1
SCHEMBL23068539 0.98 ACLY (0.95) ACLYCPT2HSPD1BLMHSPE1
Ammonia Solution, Strong SCHEMBL4780983 0.98 ACLY (0.95) ACLYCPT2HSPD1BLMHSPE1
SCHEMBL2821490 0.98 ACLY (0.95) ACLYCPT2HSPD1BLMHSPE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075731-A Gambogic acid kidney delivery system based on beta-lactoglobulin reabsorption mediation and synthesis method and application thereof 2026-05-26 CN claimed
EP-4157199-A1 METHODS AND PHARMACEUTICAL PREPARATIONS FOR ELEVATING BLOOD HEMOGLOBIN AND OXYGEN SATURATION LEVELS WITH HYDROXYCITRIC ACID Glykon Technologies Group, LLC (US) 2023-04-05 EP claimed
EP-4157254-A1 METHODS AND PHARMACEUTICAL PREPARATIONS FOR ELEVATING KETONE UTILIZATION Glykon Technologies Group, LLC. (US) 2023-04-05 EP claimed
EP-4156970-A1 REDUCING TRIGLYCERIDE LEVELS AND CORTISOL LEVELS WITH PHARMACEUTICAL PREPARATIONS Glykon Technologies Group, LLC. (US) 2023-04-05 EP claimed
CN-115006378-A Medicine for preventing or treating metabolic diseases or metabolic dysfunction diseases 西安莱格瑞生物科技有限公司 2022-09-06 CN claimed
US-20190216756-A1 ORGANIC ACIDS AS AGENTS TO DISSOLVE CALCIUM MINERALS IN PATHOLOGICAL CALCIFICATION AND USES THEREOF UNIVERSITY OF HOUSTON SYSTEM (US) 2019-07-18 US claimed
US-10285961-B2 Organic acids as agents to dissolve calcium minerals in pathological calcification and uses thereof UNIVERSITY OF HOUSTON SYSTEM (US) 2019-05-14 US claimed
US-20150297545-A1 ORGANIC ACIDS AS AGENTS TO DISSOLVE CALCIUM MINERALS IN PATHOLOGICAL CALCIFICATION AND USES THEREOF UNIVERSITY OF HOUSTON SYSTEM (US) 2015-10-22 US claimed
US-6706899-B2 TETRAHYDRO-3-HYDROXY-5-OXO-2,3-FURANDICARBOXYLIC ACID (GARCINIA ACID) DERIVATIVES MADE BY REFLUXING GARCINIA ACID WITH ALCOHOLS USING AN ACID CATALYST; PHARMACEUTICAL APPLICATIONS DEPARTMENT OF SCIENCE AND TECHNOLOGY, TECHNOLOGY BHAVAN (IN) 2004-03-16 US claimed
US-20020042528-A1 Novel acyclic chiral compound from garcinia acid and process for preparing the same DEPARTMENT OF SCIENCE AND TECHNOLOGY, TECHNOLOGY BHAVAN (IN) 2002-04-11 US claimed
CN-122075733-A Preparation method and application of linker medicine and antibody-medicine conjugate thereof 2026-05-26 CN disclosed
CN-122031713-A Preparation method and application of linker medicine and antibody-medicine conjugate thereof 乐普生物科技股份有限公司 2026-05-15 CN disclosed
US-20260124237-A1 CARTILAGE REGENERATION COMPOSITION KOBAYASHI PHARMACEUTICAL CO LTD (JP) 2026-05-07 US disclosed
CN-119816522-B 5T4 antibody drug conjugate and application thereof 上海美雅珂生物技术有限责任公司 2025-06-24 CN disclosed
CN-119894536-A GPC3 antibody drug conjugate and application thereof 乐普生物科技股份有限公司 2025-04-25 CN disclosed
US-20220248744-A1 NICOTINE MATERIALS, METHODS OF MAKING SAME, AND USES THEREOF THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK 2022-08-11 US disclosed
CN-113952329-A Application of gambogic acid in preparation of Src inhibitor and preparation of liver cancer treatment drug 广州医科大学附属第二医院 2022-01-21 CN disclosed
US-6706899-B2 TETRAHYDRO-3-HYDROXY-5-OXO-2,3-FURANDICARBOXYLIC ACID (GARCINIA ACID) DERIVATIVES MADE BY REFLUXING GARCINIA ACID WITH ALCOHOLS USING AN ACID CATALYST; PHARMACEUTICAL APPLICATIONS DEPARTMENT OF SCIENCE AND TECHNOLOGY, TECHNOLOGY BHAVAN (IN) 2004-03-16 US disclosed
US-20020042528-A1 Novel acyclic chiral compound from garcinia acid and process for preparing the same DEPARTMENT OF SCIENCE AND TECHNOLOGY, TECHNOLOGY BHAVAN (IN) 2002-04-11 US disclosed
US-6147228-A Convenient method for the large scale isolation of garcinia acid DEPARTMENT OF SCIENCE AND TECHNOLOGY GOVERNMENT OF INDIA (IN) 2000-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020042528-A1 Novel acyclic chiral compound from garcinia acid and process for preparing the same GK, ADH1A, CNR1 ACLY 1190/4885CPT2 679/4885HSPD1 4574/4885
US-20260124237-A1 CARTILAGE REGENERATION COMPOSITION CSGALNACT1, CD44, HCAR1 ACLY 3090/4885CPT2 3121/4885HSPD1 158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.