Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.54 |
| ▸ | TUBB | P07437 | 2/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9590857 | 0.86 | PKM (0.68) | PKMTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27674625 | 0.86 | PKM (0.63) | PKMTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1366438 | 0.83 | PKM (1.00) | PKMTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4780674 | 0.79 | PKM (0.70) | PKMTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2717445 | 0.77 | PKM (0.67) | PKMTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27648529 | 0.76 | PKM (0.57) | PKMTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14278743 | 0.75 | PKM (0.68) | PKMTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1516211 | 0.75 | PKM (0.64) | PKMTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27744199 | 0.74 | PKM (0.63) | PKMTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5899359 | 0.74 | PKM (0.62) | PKMTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |