Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780035 | 1.00 | TSHR (0.35) | TSHRTHRBMEN1HTTKMT2A | |
| SCHEMBL4775373 | 1.00 | TSHR (0.35) | TSHRTHRBMEN1HTTKMT2A | |
| SCHEMBL4778272 | 0.98 | ALDH1A1 (0.31) | TSHRTHRBMEN1HTTKMT2A | |
| SCHEMBL6161219 | 0.98 | TSHR (0.36) | TSHRTHRBMEN1HTTKMT2A | |
| SCHEMBL6161200 | 0.91 | MEN1 (0.35) | TSHRTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL14778543 | 0.91 | MEN1 (0.35) | TSHRTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL6160537 | 0.91 | MEN1 (0.35) | TSHRTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL14778086 | 0.91 | MEN1 (0.35) | TSHRTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL14780056 | 0.91 | MEN1 (0.35) | TSHRTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL14777998 | 0.91 | MEN1 (0.35) | TSHRTHRBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008004788-A1 | NOVEL DERIVATIVES OF CYCLIC COMPOUND AND THE USE THEREOF | WONKISOPHARM CO., LTD. (KR) | 2008-01-10 | — | — | WO | disclosed |