Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.34 |
| ▸ | CA1 | P00915 | 5/20 | 0.34 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | CA9 | Q16790 | 5/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775373 | 0.98 | TSHR (0.35) | TSHRTHRBMEN1HTTKMT2A | |
| SCHEMBL4781283 | 0.98 | TSHR (0.35) | TSHRTHRBMEN1HTTKMT2A | |
| SCHEMBL4780035 | 0.98 | TSHR (0.35) | TSHRTHRBMEN1HTTKMT2A | |
| SCHEMBL4778272 | 0.95 | ALDH1A1 (0.31) | TSHRTHRBMEN1HTTKMT2A | |
| SCHEMBL6160914 | 0.91 | ADRB2 (0.36) | TSHRMEN1KMT2AALDH1A1CA1 | |
| SCHEMBL14778543 | 0.88 | MEN1 (0.35) | TSHRTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL14780056 | 0.88 | MEN1 (0.35) | TSHRTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL6161200 | 0.88 | MEN1 (0.35) | TSHRTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL6160537 | 0.88 | MEN1 (0.35) | TSHRTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL14778086 | 0.88 | MEN1 (0.35) | TSHRTHRBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893442-B1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6054591-A | LYMPHOTROPIC ANTI-AIDS AGENT | SHIONOGI & CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0893442-A1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-01-27 | — | — | EP | disclosed |