Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2705273 | 0.86 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1POLBLMNA | |
| SCHEMBL2702360 | 0.83 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL26159159 | 0.83 | KMT2A (0.50) | KMT2AMEN1ALDH1A1POLBLMNA | |
| SCHEMBL26159160 | 0.77 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1POLBLMNA | |
| SCHEMBL2705838 | 0.76 | MEN1 (0.55) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL1292014 | 0.75 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1POLBLMNA | |
| SCHEMBL28671140 | 0.71 | KCNA3 (0.60) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL22578028 | 0.70 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL28556783 | 0.69 | MAPT (0.44) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL4729600 | 0.69 | HTT (0.43) | KMT2AMEN1ALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |