Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28549773 | 0.90 | MMP2 (0.48) | MMP2KCNN4KCNA3LMNATP53 | |
| SCHEMBL28556938 | 0.85 | MMP2 (0.43) | MAPTMMP2KCNN4KCNA3LMNA | |
| SCHEMBL28565008 | 0.84 | KCNN4 (0.59) | MMP2KCNN4KCNA3LMNACA1 | |
| SCHEMBL28549772 | 0.84 | MMP2 (0.47) | MAPTMMP2KCNN4KCNA3LMNA | |
| SCHEMBL27995397 | 0.78 | MAPT (0.50) | MAPTMMP2KCNN4KCNA3LMNA | |
| SCHEMBL533706 | 0.76 | MAPT (0.56) | MAPTKCNN4KCNA3LMNATP53 | |
| SCHEMBL31585998 | 0.76 | MAPT (0.56) | MAPTKCNN4KCNA3LMNATP53 | |
| SCHEMBL1292014 | 0.74 | ALDH1A1 (0.48) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL31585919 | 0.73 | MAPT (0.44) | MAPTMMP2KCNN4KCNA3LMNA | |
| SCHEMBL20602223 | 0.73 | MAPT (0.44) | MAPTMMP2KCNN4KCNA3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107903211-B | Preparation method of 3-halogenated-2, 3-dihydro-4-quinolinone | 上海应用技术大学 | 2021-05-11 | — | — | CN | disclosed |