Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914135 | 0.86 | FPR2 (0.32) | FPR2PROKR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4910514 | 0.82 | BACE1 (0.47) | — | |
| SCHEMBL4913370 | 0.78 | CNR1 (0.33) | FPR2PROKR1 | |
| SCHEMBL4783917 | 0.75 | PKM (0.38) | — | |
| SCHEMBL4906788 | 0.74 | BACE1 (0.45) | — | |
| SCHEMBL4919313 | 0.71 | CNR1 (0.34) | — | |
| SCHEMBL4853018 | 0.71 | BACE1 (0.32) | — | |
| SCHEMBL4912609 | 0.71 | BACE1 (0.59) | — | |
| SCHEMBL4305599 | 0.68 | BACE1 (0.46) | — | |
| SCHEMBL4901396 | 0.68 | BACE1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076046-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |