Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 5/20 | 0.33 |
| ▸ | PPARA | Q07869 | 5/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | MMP10 | P09238 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778824 | 0.86 | LPAR1 (0.42) | ADRB3KDM4EPPARGPPARAPPARD | |
| SCHEMBL4779393 | 0.85 | ESR1 (0.39) | SMN1; SMN2NPSR1LMNAKDM4EHTT | |
| SCHEMBL4904400 | 0.80 | PPARG (0.36) | PREPPPARGPPARA | |
| SCHEMBL4781589 | 0.80 | PPARG (0.36) | PREPPPARGPPARA | |
| SCHEMBL14281859 | 0.72 | PPARG (0.34) | LMNAPREPPPARGPPARA | |
| SCHEMBL7535671 | 0.70 | F2RL1 (0.46) | LMNAHTTPREPPPARGPPARD | |
| SCHEMBL4977539 | 0.69 | CA12 (0.46) | PREP | |
| SCHEMBL4780684 | 0.69 | LPAR1 (0.45) | MAPT | |
| SCHEMBL3839217 | 0.67 | CYP4F2 (0.50) | SMN1; SMN2LMNAKDM4EHTTL3MBTL1 | |
| SCHEMBL4775931 | 0.66 | ALDH1A1 (0.41) | ADRB3SMN1; SMN2LMNAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008006044-A2 | SUBSTITUTED ACID DERIVATIVES USEFUL AS ANTIDIABETIC AND ANTIOBESITY AGENTS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-10 | — | — | WO | disclosed |