Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | VDR | P11473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781591 | 0.86 | ADRB3 (0.39) | ADRB3PPARDPPARAPPARGMAPT | |
| SCHEMBL4780684 | 0.83 | LPAR1 (0.45) | LPAR1LPAR5ACHEALDH1A1TDP1 | |
| SCHEMBL4905528 | 0.80 | PPARG (0.43) | PPARAPPARGACHEALDH1A1TSHR | |
| SCHEMBL4778818 | 0.80 | PPARG (0.43) | PPARAPPARGACHEALDH1A1TSHR | |
| SCHEMBL7535671 | 0.72 | F2RL1 (0.46) | PPARDPPARGVDRALDH1A1MAPT | |
| SCHEMBL13899312 | 0.69 | PPARG (0.38) | PPARAPPARGALDH1A1TSHRKMT2A | |
| SCHEMBL4779393 | 0.69 | ESR1 (0.39) | PPARAPPARGMAPTKDM4EESR1 | |
| SCHEMBL3839217 | 0.69 | CYP4F2 (0.50) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL5292779 | 0.69 | ACHE (0.45) | ACHEALDH1A1CYP3A4 | |
| SCHEMBL4775931 | 0.68 | ALDH1A1 (0.41) | ADRB3ALDH1A1TDP1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008006044-A2 | SUBSTITUTED ACID DERIVATIVES USEFUL AS ANTIDIABETIC AND ANTIOBESITY AGENTS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-10 | — | — | WO | disclosed |