⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783078 | 0.69 | — | — | |
| SCHEMBL1875818 | 0.65 | — | — | |
| SCHEMBL4783508 | 0.64 | — | — | |
| SCHEMBL25246618 | 0.64 | AURKA (0.32) | — | |
| SCHEMBL21084229 | 0.64 | IDO1 (0.41) | — | |
| SCHEMBL6741100 | 0.63 | — | — | |
| SCHEMBL22206279 | 0.63 | — | — | |
| SCHEMBL4784423 | 0.63 | — | — | |
| SCHEMBL4781864 | 0.63 | — | — | |
| SCHEMBL4783082 | 0.63 | HMBS (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | claimed |
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | disclosed |