⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783515 | 0.78 | CHEK1 (0.32) | — | |
| SCHEMBL4782243 | 0.70 | — | — | |
| SCHEMBL4730853 | 0.68 | — | — | |
| SCHEMBL1849836 | 0.65 | POLB (0.44) | — | |
| SCHEMBL1875818 | 0.64 | — | — | |
| SCHEMBL4781673 | 0.64 | — | — | |
| SCHEMBL4779961 | 0.64 | — | — | |
| SCHEMBL101638 | 0.64 | — | — | |
| SCHEMBL4783145 | 0.63 | — | — | |
| SCHEMBL4782760 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | claimed |
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | disclosed |