Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781823 | 1.00 | SLC6A3 (0.67) | SLC6A3SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL3182249 | 1.00 | SLC6A3 (0.67) | SLC6A3SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL3180497 | 0.82 | SLC6A3 (0.64) | SLC6A3SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL3184955 | 0.81 | HIF1A (0.60) | SLC6A3SLC6A2SLC6A4HIF1AHSD17B10 | |
| SCHEMBL28321870 | 0.81 | MEN1 (0.53) | SLC6A3SLC6A2SLC6A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL20482078 | 0.80 | MEN1 (0.56) | SLC6A3SLC6A2SLC6A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL20482079 | 0.80 | MEN1 (0.56) | SLC6A3SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL3179208 | 0.80 | HIF1A (0.66) | SLC6A3SLC6A2SLC6A4HIF1AHSD17B10 | |
| SCHEMBL20828152 | 0.78 | SLC6A2 (0.64) | SLC6A3SLC6A2SLC6A4HIF1AHSD17B10 | |
| SCHEMBL3179287 | 0.78 | SLC6A2 (0.64) | SLC6A3SLC6A2SLC6A4HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |