Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3443002 | 0.93 | GPR119 (0.43) | UCHL1GPR119KLK7KDM1A | |
| SCHEMBL1795627 | 0.93 | GPR119 (0.43) | UCHL1GPR119KLK7KDM1A | |
| SCHEMBL25969334 | 0.93 | GPR119 (0.43) | UCHL1GPR119KLK7KDM1A | |
| SCHEMBL3538308 | 0.92 | GPR119 (0.43) | UCHL1GPR119KLK7KDM1A | |
| SCHEMBL28194949 | 0.89 | KLK7 (0.45) | UCHL1GPR119KLK7 | |
| SCHEMBL29997863 | 0.89 | KLK7 (0.45) | UCHL1GPR119KLK7 | |
| SCHEMBL1843454 | 0.89 | KLK7 (0.45) | UCHL1GPR119KLK7 | |
| SCHEMBL13997813 | 0.89 | KLK7 (0.45) | UCHL1GPR119KLK7 | |
| SCHEMBL8224323 | 0.89 | GPR119 (0.51) | GPR119KDM1A | |
| SCHEMBL14453328 | 0.84 | GPR119 (0.44) | UCHL1GPR119KLK7NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |