Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.51 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3442475 | 0.89 | GPR119 (0.47) | GPR119KDM4EKMT2AALDH1A1CYP3A4 | |
| SCHEMBL4781869 | 0.89 | USP30 (0.43) | GPR119KDM1A | |
| SCHEMBL4143386 | 0.86 | GPR119 (0.47) | GPR119KDM4ECYP3A4 | |
| SCHEMBL4781855 | 0.84 | DAGLB (0.46) | ADAM17DAGLBDPP4DPP7KDM4E | |
| SCHEMBL4781860 | 0.84 | DAGLB (0.46) | ADAM17DAGLBDPP4DPP7KDM4E | |
| SCHEMBL8221589 | 0.82 | GPR119 (0.43) | GPR119KDM4D | |
| SCHEMBL3443002 | 0.82 | GPR119 (0.43) | GPR119KDM1AMEN1KMT2ACYP2C9 | |
| SCHEMBL1795627 | 0.82 | GPR119 (0.43) | GPR119KDM1AMEN1KMT2ACYP2C9 | |
| SCHEMBL25969334 | 0.82 | GPR119 (0.43) | GPR119KDM1AMEN1KMT2ACYP2C9 | |
| SCHEMBL3538308 | 0.81 | GPR119 (0.43) | GPR119KDM1AMEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |