Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.56 |
| ▸ | SMO | Q99835 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732268 | 0.80 | FASN (0.59) | SMN1; SMN2MAPTMEN1KMT2AGAA | |
| SCHEMBL4735643 | 0.76 | FASN (0.58) | MAPK14MAPTLMNAALDH1A1 | |
| SCHEMBL4732879 | 0.75 | SMN1; SMN2 (0.64) | MAPK14SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL6475916 | 0.74 | MAPK14 (0.66) | MAPK14SMOMAPTMEN1KMT2A | |
| SCHEMBL31531892 | 0.73 | TSHR (0.69) | SMN1; SMN2MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL26990533 | 0.73 | TSHR (0.69) | SMN1; SMN2MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL4737601 | 0.73 | FASN (0.59) | MAPK14SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL2968436 | 0.72 | MAPK14 (0.82) | MAPK14SMOMAPTMEN1KMT2A | |
| SCHEMBL6477445 | 0.72 | MAPK14 (1.00) | MAPK14SMOMAPTMEN1KMT2A | |
| SCHEMBL6780689 | 0.72 | MAPK14 (0.64) | MAPK14SMOSMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |