Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783890 | 0.92 | GPR119 (0.32) | GPR119MAPK14NR1I2 | |
| SCHEMBL4782655 | 0.86 | GPR119 (0.33) | GPR119MAPK14NR1I2 | |
| SCHEMBL4783259 | 0.82 | MAPK14 (0.34) | MAPK14NR1I2 | |
| SCHEMBL4782670 | 0.82 | RAF1 (0.39) | MAPK14 | |
| SCHEMBL4783260 | 0.82 | MAPK14 (0.31) | MAPK14NR1I2 | |
| SCHEMBL4781042 | 0.82 | BRAF (0.32) | MAPK14NR1I2 | |
| SCHEMBL4781875 | 0.81 | SCN10A (0.34) | MAPK14NR1I2 | |
| SCHEMBL4799766 | 0.80 | DDT (0.32) | MAPK14NR1I2 | |
| SCHEMBL4781726 | 0.76 | MAPK14 (0.41) | MAPK14 | |
| SCHEMBL4781600 | 0.76 | TEK (0.38) | GPR119NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |