Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783254 | 0.90 | MAPK14 (0.35) | MAPK14 | |
| SCHEMBL4781875 | 0.88 | SCN10A (0.34) | MAPK14NR1I2RAF1BRAF | |
| SCHEMBL4781042 | 0.86 | BRAF (0.32) | MAPK14NR1I2RAF1BRAF | |
| SCHEMBL4783259 | 0.86 | MAPK14 (0.34) | MAPK14NR1I2BRAF | |
| SCHEMBL4782038 | 0.84 | TEK (0.39) | NR1I2RAF1BRAF | |
| SCHEMBL4783890 | 0.83 | GPR119 (0.32) | MAPK14NR1I2RAF1BRAF | |
| SCHEMBL4799766 | 0.82 | DDT (0.32) | MAPK14NR1I2RAF1BRAF | |
| SCHEMBL4782086 | 0.82 | GPR119 (0.32) | MAPK14NR1I2 | |
| SCHEMBL4782033 | 0.81 | NR1I2 (0.35) | NR1I2 | |
| SCHEMBL4730327 | 0.81 | RAF1 (0.41) | MAPK14RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |