⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844734 | 0.75 | PGR (0.36) | — | |
| SCHEMBL1875818 | 0.68 | — | — | |
| SCHEMBL4783078 | 0.68 | — | — | |
| SCHEMBL4731433 | 0.67 | — | — | |
| SCHEMBL703646 | 0.66 | LMNA (0.43) | — | |
| SCHEMBL17254440 | 0.66 | ESR1 (0.33) | — | |
| SCHEMBL6741100 | 0.66 | — | — | |
| SCHEMBL3324502 | 0.65 | CYP2A6 (0.39) | — | |
| SCHEMBL13545606 | 0.65 | GAA (0.50) | — | |
| SCHEMBL6741105 | 0.64 | NOTUM (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | claimed |
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | disclosed |