Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884449 | 0.78 | PPARA (0.47) | PPARGPPARA | |
| SCHEMBL4893501 | 0.77 | PPARA (0.44) | PPARGMEN1KMT2ANPC1PPARA | |
| SCHEMBL4892388 | 0.76 | PPARA (0.48) | LMNAPPARGKMT2APPARA | |
| SCHEMBL4896548 | 0.75 | ALDH1A1 (0.42) | SMN1; SMN2LMNAPSMD10STAT3PPARG | |
| SCHEMBL4896669 | 0.75 | RXFP1 (0.44) | SMN1; SMN2PSMD10PPARGKMT2APPARA | |
| SCHEMBL4889147 | 0.75 | ALDH1A1 (0.53) | PPARGMEN1KMT2APPARA | |
| SCHEMBL4897320 | 0.75 | KDM4E (0.44) | LMNAPPARGGAAMEN1KMT2A | |
| SCHEMBL4888392 | 0.74 | KDM4E (0.51) | SMN1; SMN2LMNAGAAMEN1KMT2A | |
| SCHEMBL4885887 | 0.73 | RAB9A (0.42) | SMN1; SMN2PPARGMEN1KMT2APPARA | |
| SCHEMBL241884 | 0.71 | CA1 (0.52) | SMN1; SMN2LMNASTAT3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |