Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.49 |
| ▸ | FAP | Q12884 | 1/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | HRH2 | P25021 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726741 | 0.77 | DPP4 (0.75) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL8216389 | 0.77 | DPP4 (0.75) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL4726743 | 0.77 | DPP4 (0.75) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL561829 | 0.77 | MAOB (0.61) | MAOBPARP10 | |
| SCHEMBL561827 | 0.77 | MAOB (0.61) | MAOBPARP10 | |
| SCHEMBL4801659 | 0.77 | DPP4 (0.48) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL8218015 | 0.77 | DPP4 (0.48) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL8216131 | 0.77 | DPP4 (0.48) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL8335153 | 0.76 | DPP4 (0.82) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL7371920 | 0.74 | NPC1 (0.58) | DPP4DPP7FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029217-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-03-13 | — | — | WO | claimed |
| WO-2008029217-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-03-13 | — | — | WO | disclosed |