Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.44 |
| ▸ | FAP | Q12884 | 4/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801659 | 1.00 | DPP4 (0.48) | DPP4LTA4HNPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL4728792 | 0.90 | LTA4H (0.47) | DPP4LTA4HNPC1RAB9AMEN1 | |
| SCHEMBL8216131 | 0.84 | DPP4 (0.48) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL4781929 | 0.82 | DPP4 (0.48) | DPP4LTA4HNPC1RAB9AMEN1 | |
| SCHEMBL8219658 | 0.82 | DPP4 (0.48) | DPP4LTA4HNPC1RAB9AMEN1 | |
| SCHEMBL8216166 | 0.80 | DPP4 (0.43) | DPP4LTA4HALDH1A1DPP7FAP | |
| SCHEMBL4782430 | 0.77 | DPP4 (0.52) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL4782189 | 0.76 | DPP4 (0.49) | DPP4LTA4HNPC1RAB9AMEN1 | |
| SCHEMBL8213925 | 0.76 | DPP4 (0.49) | DPP4LTA4HNPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL6491094 | 0.75 | MEN1 (0.59) | LTA4HNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029217-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-03-13 | — | — | WO | disclosed |