Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896191 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL29613269 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL19434734 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL4430194 | 0.73 | BAD (0.50) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL3277941 | 0.72 | ATM (0.31) | ATMCYP2A6 | |
| Hydrochloric Acid SCHEMBL11496936 | 0.71 | BAD (0.53) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Iodide SCHEMBL4434756 | 0.71 | BAD (0.49) | ALDH1A1 | |
| SCHEMBL13043235 | 0.71 | KDM4E (0.56) | ALDH1A1KDM4ELMNAALPGHPGD | |
| Bromide SCHEMBL1866676 | 0.71 | BAD (0.49) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL5051912 | 0.70 | HTT (0.47) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103319694-B | Conjugated polymer containing pyrido phenanthridines-5-ketone and preparation method thereof and application | 华南理工大学 | 2016-06-29 | — | — | CN | claimed |
| CN-103319694-A | Conjugated polymer containing pyridinophenanthridine-5-ketone and preparation method and application thereof | UNIV SOUTH CHINA TECH | 2013-09-25 | — | — | CN | claimed |
| US-20050187278-A1 | Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors | PHARMACIA CORPORATION (US) | 2005-08-25 | — | — | US | claimed |
| WO-2005020926-A2 | TREATMENT OR PREVENTION OF VASCULAR DISORDERS WITH COX-2 INHIBITORS IN COMBINATION WITH CYCLIC AMP-SPECIFIC PHOSPHODIESTERASE INHIBITORS | PHARMACIA CORPORATION (US) | 2005-03-10 | — | — | WO | claimed |
| CN-119241435-A | 6-Trifluoro methylthiophenanthrene Synthesis method of pyridine compound | 西北师范大学 | 2025-01-03 | — | — | CN | disclosed |
| CN-103319694-B | Conjugated polymer containing pyrido phenanthridines-5-ketone and preparation method thereof and application | 华南理工大学 | 2016-06-29 | — | — | CN | disclosed |
| CN-103319694-A | Conjugated polymer containing pyridinophenanthridine-5-ketone and preparation method and application thereof | UNIV SOUTH CHINA TECH | 2013-09-25 | — | — | CN | disclosed |
| CN-1980899-B | Quinazolinone derivatives as parp inhibitors | JANSSEN PHARMACEUTICA NV | 2013-07-24 | — | — | CN | disclosed |
| CN-102206180-B | Substituted 6-cyclohexylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(ADP-ribose) polymerase inhibitors | JANSSEN PHARMACEUTICA NV | 2013-05-29 | — | — | CN | disclosed |
| CN-1980913-B | quinazolinedione derivatives as PARP inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2011-12-14 | — | — | CN | disclosed |
| CN-102206180-A | Substituted 6-cyclohexylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(ADP-ribose) polymerase inhibitors | JANSSEN PHARMACEUTICA NV | 2011-10-05 | — | — | CN | disclosed |
| CN-1980674-B | Phthalazine derivatives as parp inhibitors | JANSSEN PHARMACEUTICA NV | 2011-05-25 | — | — | CN | disclosed |
| EP-0682666-A4 | 2-PHENANTHRIDINYL CARBAPENEM ANTIBACTERIAL AGENTS. | MERCK & CO INC (US) | 1996-02-21 | — | — | EP | disclosed |
| EP-0682667-A4 | 2-PHENANTHRIDINYL CARBAPENEM ANTIBACTERIAL AGENTS. | MERCK & CO INC (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0682667-A1 | 2-PHENANTHRIDINYL CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO. INC. (US) | 1995-11-22 | — | — | EP | disclosed |
| EP-0682666-A1 | 2-PHENANTHRIDINYL CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO. INC. (US) | 1995-11-22 | — | — | EP | disclosed |
| US-5336674-A | Grampositive bacteria, particularly methicillin-resistant Staphylococcus | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | disclosed |
| WO-1994017066-A1 | 2-PHENANTHRIDINYL CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO., INC. (US) | 1994-08-04 | — | — | WO | disclosed |
| WO-1994017065-A1 | 2-PHENANTHRIDINYL CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO., INC. (US) | 1994-08-04 | — | — | WO | disclosed |
| US-5328904-A | Active against methicillin resistant Staphylococcus | MERCK & CO., INC. (US) | 1994-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187278-A1 | Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors | PDE2A, PDE3A, PDE3B | ATM 2492/4885ALDH1A1 987/4885HSD17B10 885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.