SCHEMBL4430194

SCHEMBL4430194

C[n+]1cc2ccccc2c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
BAD Q92934 2/20 0.50
ALDH1A1 P00352 2/20 0.42
CYP2A6 P11509 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
ALPG P10696 1/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11496936 0.98 BAD (0.53) BADALDH1A1CYP2A6TSHRHSD17B10
Iodide SCHEMBL4434756 0.98 BAD (0.49) BADALDH1A1
Bromide SCHEMBL1866676 0.98 BAD (0.49) BADALDH1A1CYP2A6TSHRHSD17B10
Perchlorate SCHEMBL3903408 0.92 RAB9A (0.50) BADHTTSMN1; SMN2
Trifluoromethanesulfonic Acid SCHEMBL20495457 0.83 GPR3 (0.39) BAD
Hydrochloric Acid SCHEMBL11302277 0.75 BAD (0.57) BADALDH1A1HTTSMN1; SMN2
SCHEMBL4782479 0.73 ATM (0.43) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL19434734 0.73 ALDH1A1 (0.42) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL31614554 0.72 RAD52 (0.54) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL16736485 0.72 RAD52 (0.54) ALDH1A1CYP2A6TSHRHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112142665-A Natural-source thioredoxin reductase inhibitor with novel chemical type and application thereof 兰州大学 2020-12-29 CN claimed
CN-112142665-A Natural-source thioredoxin reductase inhibitor with novel chemical type and application thereof 兰州大学 2020-12-29 CN disclosed
US-20090173693-A1 LYOTROPIC LIQUID CRYSTAL MEMBRANES BASED ON CROSS-LINKED TYPE I BICONTINUOUS CUBIC PHASES NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2009-07-09 US disclosed
US-6241873-B1 SOLID ELECTROLYTE FORMED BY HEAT TREATING POLYMER HAVING QUATERNARY AMMONIUM GROUP IN ITS MAIN CHAIN AND HAVING HALIDE ION AS COUNTER ION, AND METAL HALIDE AT AT LEAST 100 DEGREES C. TDK CORPORATION (JP) 2001-06-05 US disclosed